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Granulating & Agglomerating
Spray Granulation |
Spray granulation
Single-step granulation from an active powder
The powder to be granulated is suspended in the heated air of a fluid bed,
and a liquid binder sprayed from nozzles positioned above (Top Spray Granulator™) or below (Precision Granulator™)
Capacity: from 50g to several ton/batch or several
ton/hr |
High-shear granulation
High Shear Granulation |
Mixing and granulation
The high-shear granulation process combines the active powder with a binder
solution using a high-speed mixing blade and chopper. The Pharma Matrix ™ is a stand-alone mixer / granulator. The
GP System™ is a modular Building
Block System™ offering user-selectable options for mixing, high-shear
granulating, vacuum or microwave drying and melt or wet pelletizing.
Capacity: from 36 to 1,800 L
Pma™ Pharma Matrix™ Mixer
/ Granulators |
Ultima™
600 |
High-shear granulation
Mixing, granulation, and drying
The basic Gral design is a high shear mixer granulator which allows the
processes of dry mixing, wet mixing, granulation, and drying in a totally
contained environment. The most important features of this basic design are the
top-driven mixer and chopper, the removable bowl, and the "through-the-wall"
installation of the larger machines.
Capacity: from 10 L to 1200 L |
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Precision Coater™ |
Precision Coater™(Patented)—Process for Applying Thin
Coatings to Fine Powders
Niro has developed a process which allows very thin coatings (as little as a
few hundred atoms thick) to be applied to fine powders. We have coated powders
with a mean diameter of 15 microns up to 1000 microns (1 mm) or more. We have
also coated very irregularly shaped particles.
The process works by suspending and tumbling the particles in a high
velocity gas flow and applying the coating as a fine mist. Both liquid and
solid powder coatings have been applied with the process. |
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PRECISION GRANULATION™ ( Patented )
A NEW
PROCESS FOR PRECISION CONTROL OF AGGLOMERATION AND COATING
While conventional top spray fluid bed granulation is a well-established
process, there are a number of problems with this technology. Niro has
developed a new granulation process, called Precision
Granulation™ ( Patented ) which offers:
- Better control of granule properties
- The ability to granulate soluble and hygroscopic materials
- The ability to granulate fine particles
- A more stable process
- Faster processing times
The Niro Precision Granulation™ ( Patented )
process is the result of intensive study of the flow behavior of particles
suspended in gas streams. |